Isoluminol derivatives are popular options for tagging molecules in luminescent assays. The purpose of this study is to synthesize a new brighter isoluminol derivative by the addition of a methyl group on the isoluminol aromatic ring as well as a polymerizable norbornene fused to a pyrrolidine. In this project the N-methylphthalimide isoluminol precursor has been successfully synthesized in six steps in but in low yields. This compound has been well characterized with a variety of NMR experiments. The target molecule of this research, an isoluminol derivative, will be synthesized from the N-methylphthalimide precursor by heating with hydrazine in ethanol. The quantum yield of this novel isoluminol derivative will be compared to other known isoluminol compounds.

Synthesis of a novel polymerizable isoluminol derivative

245th National Meeting (2013)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.