Much cell-cell communication is mediated by proteins and processes located at the plasma membranes of the participating cells. Thus, biomimetic membrane surfaces have been recognized for many years as an ideal tool to study such communication processes or to create active, biocompatible interfaces with living cells. However, much about the basic membrane �cell interactions in such systems is unknown. Furthermore, reliable and general schemes to decorate artificial membranes with the necessary proteins for cell attachment and communication remain a challenge. Here, we present results that elucidate the cellular responses to biomimetic membranes of different properties. In addition, a modular scheme for protein augmentation of membranes that is based on site specific lipidation is discussed.

Biomimetic membranes in basic science and application

245th National Meeting (2013)

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