The organo-arsenic compounds roxarsone and para-arsanilic acid are used in farming sectors to control disease among livestock. Since workers in animal feed-producing factories can be exposed to these potentially toxic compounds, methods for their analysis are necessary. The purpose of this research is to develop a method using high performance liquid chromatography (HPLC) for the detection of para-arsanilic acid in air. The HPLC used a C-18 column and a mobile phase of 60% water, 38 % methanol, and 2% acetic acid. To identify the optimal filter for collection of the compounds, polyvinyl chloride (PVC), glass fiber, and polytetrafluoroethylene (PTFE) filters were studied. Using the optimal filter, PVC, a twenty-eight day storage study was performed which yielded acceptable recoveries for filters spiked at levels corresponding to the Permissible Exposure Limit (PEL). Recoveries for varying levels of the PEL on filters will be reported as well as the method limit of detection.

Examination of high performance liquid chromatography methods pertaining to the analysis of <i>para</i>-arsanilic acid

245th National Meeting (2013)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.

Examination of high performance liquid chromatography methods pertaining to the analysis of para-arsanilic acid