The purpose of this research was to incorporate potassium phosphate as a buffering agent to combat tampering with urine in standard drug testing.  When hydrogen peroxide and peroxidase are added to a urine sample the chemicals will react with certain drugs and alter their conformation.  This alteration will then prevent the drug from appearing on a test.  This research examined the effect these chemicals had on morphine extracted from poppy seeds via GC Mass Spectrometry.  Based on the above research methods I will be looking to see that the addition of hydrogen peroxide and peroxidase did in fact prevent detection of the morphine.  Moreover, the potassium phosphate served as a successful buffer in the system and allowed for the detection of morphine in a synthetic urine sample.

Use of potassium phosphate as a buffer for hydrogen peroxide and peroxidase in urine analysis for morphine

245th National Meeting (2013)

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