Metal noble nanoparticles such as: gold, silver and copper have been used in several biological, technological and medical applications. Our research focused in the synthesis of noble metals nanoparticles functionalized with antibiotics. We prepared the noble metals nanoparticles using two different reducing agents, ascorbic acid and sodium borohydride. The gold nanoparticles show an absorption band between 500nm and 550nm, silver nanoparticles show a band between 400 to 450 and the copper nanoparticle show the band between the 550nm to 600nm. Then, we interacts the silver and gold with three different antibiotics (cephalexin, ciprofloxacin and clindamycin). After the addition of the antibiotics to the colloidal silver and gold nanoparticles sample, we observed a change in absorption, a red shift and the creation of the new peak. The interaction of the antibiotics with Cu nanoparticles will be presented. Concentrations profiles are evaluated to establish the sensitivity and selectivity of the method.

Functionalization and characterization of noble metals nanoparticles with antibiotics

245th National Meeting (2013)

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