Hypertension is often referred to as the �silent killer�, as it can remain asymptomatic for many years, manifesting later in life as a myriad of other diseases. Cardiovascular diseases, diabetes, peripheral artery disease (PAD), cerebrovascular diseases and kidney failure are some of the illnesses associated with hypertension.  The leaves of Artocarpus communis (breadfruit) have been used in Jamaica as a folk medicinal treatment for hypertension.  Recently there have been anecdotal reports supporting this usage.  In our preliminary studies the brewed tea extract of the green and yellow leaves of Artocarpus communis caused a 20 � 30 mmHg reduction in the mean arterial pressure in angiotensin II induced hypertensive rats.  Several known flavanoids have been identified from the aqueous extracts.  The extracts also displayed antioxidant and anti-inflammatory potential.  The in vitro and in vivo assays, as well as the identification of the constituents of the brewed tea, are discussed.

Antihypertensive metabolites from <i>Artocarpus communis</i>

245th National Meeting (2013)

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Antihypertensive metabolites from Artocarpus communis