Numerous viral infections and life threatening diseases are characterized by a specific mRNA expression pattern, making it a reliable target for diagnostics and drug therapies.  While focusing on the fast acting and highly specific characteristics necessary when creating worthwhile diagnostics, we have designed tools suitable for detecting disease-specific mRNA.  The design tools include a combination of molecular beacons with zinc finger-fluorescent protein fusions for fluorescent signaling upon mRNA target binding.  Ultimately the design allows for simple construction, easy operation, and modular mRNA targeting capabilities.

New molecular probes for disease-specific mRNA detection

245th National Meeting (2013)

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