Carbohydrate structures are drawn in a wide variety of ways � perspective chairs, Haworth projections, Fischer projections � in the literature and hence in public chemistry databases. The stereochemistry detection algorithms used in structure registration, however, cannot handle most carbohydrate depictions. We explore the consequences of this for large public chemistry databases and demonstrate automated algorithms for correct detection of sugar stereochemistry and discuss our implementation in the ChemSpider Validation and Standardization Platform.

Carbohydrate structure representation and public chemistry databases

245th National Meeting (2013)

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