Past decades saw the upcoming application of transcutaneous monitoring in neonatology. The noninvasive approach overcomes the demerit of the painful nature of blood sampling. Our work focuses on this technique in the simultaneous noninvasive measurement of tcpO2 and tcpCO2 (transcutaneous partial pressure of oxygen and carbon dioxide). The gases passively diffusing out of the porcine skin (neonate mimic) are collected by a small chamber, which connects the CO2 and O2 sensors to measure the gas concentrations. These measurements are based on initial rate of diffusion and take only a few minutes unlike the mass transfer equilibrium-based measurements which take around 20-25 minutes.  Preliminary experiments conducted on adult skin show that physical activities, food intake and breathing patterns are influential factors for the amount of CO2 evolving from the human skin. The measurement parameters like sampler area, measurement location, subject position and movement are studied from a series of subsequent trials.

Rate-based non invasive monitoring of transcutaneous gases

245th National Meeting (2013)

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