Our primary focus is to establish a new catalytic system for the direct aroylation reaction of aryltrifluoroborates. We are using various types of potassium aryltrifluoroborates as starting materials. These boron reagents are new entity in cross-coupling reaction for ketone synthesis. Most recently, in our laboratory, organotrifluoroborates compounds are employed in direct aroylation reaction for the synthesis of chalcones1 and crotonophenones.2. In this work, new catalyst system has been developed and it is used to synthesize various fluoro-substituted aromatic ketones by cross-coupling reaction of aryltrifluoroborates and aroyl chloride. These results will be presented.ReferencesPalladium-catalyzed direct cross-coupling of potassium styryltrifluoroborates and benzoyl chlorides�a one step method for chalcone synthesis. Al-Masum, M.; Ng, E.; Wai, M. Tetrahedron Lett. 2011 , 52, 1008.A New organic transformation by introducing crotyl/allyltrifluoroborates in cross-coupling reaction with aroyl chlorides. Al-Masum, M.;Liu, K-Y. Tetrahedron Lett. 2011 ,52, 5090.

Microwave irradiated Pd-catalyzed direct aroylation reaction of aryltrifluoroborates with aroyl chloride

245th National Meeting (2013)

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