The catalyzed enhancement of CO2 hydration is a critical component of efficient CO2 capture. We are exploring complexes of zinc(II) and similar metal ions with ligands such as 1,4,7,10-tetraazacyclododecane (cyclen), 5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane (tet a), tris(benzimidazolylmethyl)amine (BIMA) and anionic tris(pyrazolylborates) that mimic the enzyme, carbonic anhydrase. We utilize benign, weakly coordinating counterions PF6-, BF4-, Cl-, CH3COO-, NO3- andCF3SO3- in order to avoid hazardous perchlorate salts. However, chloride, acetate and triflate coordinate to the metal centers. Tetrafluoroborate ligand undergoes further reactions in aqueous solvents. Hexafluorosilicate, which spontaneously forms when other �inert� fluorinated counterions attack glass reaction vessels, shows no tendency to coordinate to Zn(II). [Zn(cyclen)(H2O)][SiF6]�2H2O and related complexes catalyze CO2 hydration in aqueous solvent mixtures under both pH-drop screening and stopped-flow conditions.

Synthesis and characterization of carbonic anhydrase active-site mimics for CO<sub>2 </sub>hydration

245th National Meeting (2013)

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Synthesis and characterization of carbonic anhydrase active-site mimics for CO2 hydration

Synthesis and characterization of carbonic anhydrase active-site mimics for CO₂hydration