Electrostatic forces are crucial for many key biochemical processes. For example all energy transduction processes, such as catalysis, proton transport, electron transfer and ion homeostasis involve electrostatic interactions. Similarly, all salt and pH-dependent processes are mostly driven by electrostatics. The goal of this symposium is to bring together wet- and dry-lab researchers with common interests in understanding the electrostatic effects in biological macromolecules and to forge new collaborations or strengthen ongoing collaborations between investigators. Presentations that focus on utilizing and developing different experimental and computational methods will reveal the strengths and weaknesses of these approaches and will contribute to further improvements. The symposium aims to identify important new questions for which experiment is necessary for physical insight, to guide extension of theoretical and computational models, and to provide quantitative data for benchmark of models.

Electrostatics and polarization effects in biophysical chemistry: In silico, in vitro, and in vivo

246th National Meeting (2013)

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