ADME (absorption, distribution, metabolism, and excretion) studies play an important role in developing and registering veterinary drugs for use in animal health. Such studies assist in selecting formulations, determining the fate of the active ingredients, and supporting the safety or efficacy of the drugs. Regulatory agencies require information about ADME before a product can be approved for use. For food producing animals, human food safety also must be established. Antibiotics, antiparasitics, and analgesics provide examples of product classes that maintain or enhance the well-being of animals and for which ADME forms a key component in their development and registration.

Role of ADME studies in veterinary drug development and registration

246th National Meeting (2013)

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