Nanoparticles have gained a lot of interest due to their wide applications in the field of biomedical and pharmaceutical. The applications of nanoparticles are due to their unique optical properties when they are reduced to their nanoscale size range. Gold is commonly used to form nanoparticles because it is biocompatible, non-toxic and chemically stable. Various biomolecules can be capped onto gold surface which can then be used for different biological purposes. Carbohydrates (sugars) are of prime interest. Carbohydrates are classified into different types based on the length of the sugar such as monosaccharides, disaccharides and oligosaccharides. It is interesting to understand the effect on activity of such carbohydrates when they are capped onto gold to form carbohydrate gold nanoparticles (C-AuNP). We present a novel single step biofriendly process for synthesis of C-AuNP's where in carbohydrate is directly capped onto gold without the use of any secondary capping/stabilizing agent. Our study focuses on the effect of different lengths of sugars on the formation, antibacterial activity and catalytic activity of C-AuNP's.  Three different sugars such as fructose (monosaccharide), sucrose (disaccharide) and maltotriose (trisaccharide) are used for this study. Characterization of nanoparticles is done by using various analytical techniques such as transmission electron microscope, FTIR, UV-Vis spectroscopy and SEM-EDS. To determine the antibacterial activity of different sugar capped gold nanoparticles, various antimicrobial assays are performed such as turbidimetry assay, spread plate assay, XTT assay and alamar blue assay. The catalytic activity is performed by using reduction of nitrophenol, a toxic pollutant.    Address for correspondence : Department of Chemistry, Western Kentucky University,     Bowling Green, KY 42101.Phone: (267)-324-6516                                                Email: yogesh.kherde463@topper.wku.edu

Green synthesis of sugar capped gold nanoparticles using various types of sugars and evaluation of its catalytic activity

246th National Meeting (2013)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.