Xenitorin A is a compound produced in limited supply by nature that selectively kills lung cancer cells.  The small quantity provided by nature has been sufficient to demonstrate its cytotoxicity but has not been sufficient to enable studies into its mechanism of action.  We present our efforts to synthesize xenitorin A and related xenitorin species through the preparation of a key bicyclic intermediate.

Efforts toward the synthesis of xenitorin A

246th National Meeting (2013)

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