Proteins are based on a limited library of monomers, i.e. twenty amino acids, providing a large variety of materials with well-defined characteristics and properties due to the specific sequencing of the amino acids. However, the control of the primary structure of synthetic polymers accessible from a wide range of monomers is more arduous to attain. Few research groups have developed techniques to approach the degree of sequence control existing in proteins. This presentation will focus on an iterative approach inspired by solid-phase peptide synthesis introducing features precisely localized on the oligomer backbone.

Design of novel sequence-controlled oligomers

246th National Meeting (2013)

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