Dozens of drug terminologies and resources capture the drug and/or drug class information, ranging from their coverage and adequacy of representation. No transformative ways are available to link them together in a standard way, which hinders data integration and data representation for drug-related clinical and translational studies. In the meantime, ontology design and representation being widely used in the translational research offers more capabilities to discovery novel associations among entities underneath and consistency checkup.  In this paper, we introduce a standardized drug and drug class network construction that integrates multiple drug terminological resources, using Anatomical Therapeutic Chemical (ATC) and National Drug File Reference Terminology (NDF-RT) as network backbone, and expanding with RxNorm and Structured Product Label (SPL). Meta-ontology will be established to capture drug, drug class and drug relevant information, in addition to the relationship among these entities. Instance layer will be built on the top of the meta-ontology.

Standardized drug and pharmacological class network in ontology representation

246th National Meeting (2013)

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