The �-Lactam is the central core unit of various antibiotics and is also an important precursor of various biological systems. The synthesis of the optically active stereodefined �-lactam is one of the major challenges to the organic chemists. Herein we present the highly stereoselective In(III)-induced facile ring opening of the 1,2-anhydrosugar with 3-amino azetidinone.

In(III)-catalyzed amino glycosidation of 1,2-anhydrosugar with 3-amino azitedinone: A novel method for optical resolution

247th National Meeting (2014)

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