Reactions of carbohydrates in organic solvents typically require protection of the hydroxyl groups as non-polar-moieties to enhance their solubility. Later, a subsequent deprotection step must be carried out. We are interested in the cycloaddition reactions of glycals.  We report our results of acid catalyzed reactions of unprotected D-glucal in ionic liquids in the presence of different dienes. These reactions lead to various cyclic sugar adducts in modest yields as well as, furan diol as a by-product.

Synthesis of cyclic compounds from D-glucal using ionic liquids

247th National Meeting (2014)

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