This presentation will focus on a variety of biosensing applications with charged conjugated polyelectrolytes (CPE) and oligomers (OPE) comprising a small number of repeat units of some of the larger CPE.  Both types of material have in common their properties of being soluble in aqueous media but simultaneously being very hydrophobic.  For the CPE we have taken advantage of their ability to coat irreversibly oppositely charged surfaces of glass and latex.  For the OPE we find their ability to penetrate and bind with charged hydrophobic sites reversibly or irreversibly offers some rather unique sensing applications.  For these applications we can take advantage of the strong fluorescence of both CPE and OPE and the sensitivity of the fluorescence to both specific quenching and environmental effects.

Biosensing with charged conjugated phenylene ethynylene polymers and oligomers

247th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.