The traditional line of thought in pharma is that so-called 'Small Molecules' are the problems of Chemists.  By contrast, biologics (oligonucleotides, oligosaccharides, glycoproteins) are seen to be in the purview of biology and biologists.  In this lecture we will describe some striking progress in the application of new chemistry to the synthesis of erstwhile 'biologics.'

Award Address  (Ralph F. Hirschmann Award in Peptide Chemistry sponsored by Merck Research Laboratories). Biologics by chemical synthesis

247th National Meeting (2014)

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