Metal-catalyzed silylene transfer reactions deliver the t-Bu2Si unit to a range of organic substrates. These reactions can be used for the stereoselective synthesis of a range of strained compounds. For example, silylene transfer to unsaturated epoxides resulted in insertion into the carbon�oxygen bond. The resulting allylic silanes reacted with aldehydes to form products with a trans double bond or an allene unit in an eight-membered ring. Silylene transfer to dienes provides vinylsilacyclopropanes, which react to form products with trans double bonds in seven-membered rings. The structures and reactivities of these products will be discussed.

Silylene transfer reactions as new methods for stereoselective synthesis

247th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.