The serendipitous discovery of anticancer activity of Cisplatin by Dr. Barnett Rosenberg, Loretta Van Camp and co-workers at Michigan State University (1960's) led to the world-wide use of one of the most important anticancer drugs in the history of cancer chemotherapy.    The clinical success of Cisplatin, the first metal-based anticancer drug approved by the FDA (1978), inspired a renaissance in the field of Contemporary Bioinorganic Chemistry. This talk will chronologically highlight the fascinating details of the discovery of Cisplatin1-4, a 5-year effort.The discovery is a prime example of the optimal use of the scientific method of observation, hypothesis and the testing of hypotheses

Serendipity and the prepared mind: The discovery of the antitumor drug, cisplatin

247th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.