The intercross between chemistry and biology can offer opportunities for controllable synthesis of nanomaterials. Herein, we give an example of a new strategy of �Live Cell Synthesis by Space-Time Coupling� of intracellular irrelated biochemical reactions of live cells to controllably synthesize nanomaterials for biolabeling. By such a new strategy we have successfully and controllably realized the desired synthesis of fluorescent CdSe nanocrystals with diverse monocolours of fluorescence that can never occur in live cells in nature. We also have successfully extended such a strategy/principle from the intracellular to mimetic systems, i.e. to construct quasi-biosystems for synthesis, and established multiple methods to synthesize nanomaterials for biolabeling under mild conditions, such as water-dispersible ultrasmall near-infrared Ag2Se, near-infrared PbSe nanocube and nanocage QDs, Au nanoparticles, Au-Ag alloy nanoparticles, Au clusters, and so on. In this presentation we will give a brief introduction to the synthesis, mechanism and beyond.

On synthesis of CdSe quantum dots in live cells: Synthesis, mechanism, and beyond

247th National Meeting (2014)

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