By doping carbon nanotubes it is possible to alter significantly the electronic, mechanical and chemical properties of the tubes. In this context, it will be demonstrated that Ag, ZnO, Au and TiO2, particles could be easily anchored on the surface of N-doped nanotubes using various wet chemical approaches. The bio-applications of CNx nanotubes will also be described in detail. In particular, comparative toxicological studies of CNx MWNTs and pure carbon multi-walled nanotubes (MWNTs) on mice and using amoeba cells reveal that CNx tubes appear to be far less harmful. Interestingly, pure MWNTs appeared to be lethal at all doses tested for intratracheal instilation, whereas CNx MWNTs were not. Cellular assays using Ag-CNx MWNT systems also revealed marginal toxicity after 24h, and full cellular recovery was observed at 48h based on an MTS assay. Therefore, Ag-nanotube systems appear to be very different from isolated dispersed Ag-NPs. Finally, it will be demonstrated that microfluidic devices constructed using arrays of carbon nanotubes could be successfully used to separate plasma from blood and also as an efficient biomarker separation tool.

Metallic nanoparticles anchored on nanotubes: Functional and biocompatible materials and nanomedicine devices

247th National Meeting (2014)

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