In this collaborative project, the concepts of Analytical Method Transfer (AMT) have been integrated in the undergraduate analytical chemistry curriculum at St. John Fisher College (SJFC) and Kennesaw State University (KSU). Students and faculty at SJFC and KSU have developed and integrated three novel laboratory experiments that involve AMT. The laboratory experiments are: 1) dissolution testing and UV analysis of ibuprofen tablets, 2) dissolution testing and HPLC analysis of glucosamine tablets, and 3) dissolution testing and FAAS analysis of potassium gluconate tablets. The first two of these analytical methods have been transferred to the other school to confirm the validation - hence perform an AMT as found in the real world. POGIL-based lecture and lab exercises will be developed using the validated data to be tested at other schools. The POGIL exercises will walk the students at other schools through the steps of AMT, enabling them to determine whether the transfer was successful or not. We shall compare learning gains between classes that have the instrumentation and those that do not. Both groups of students were evaluated with similar expected student learning outcomes and assessment methods. Pre/posttests, interviews and observations were used to present the findings from the evaluation activities. Preliminary data analysis based on a nonparametric statistical analysis of the pre/posttest revealed learning gains by students and content analysis of the interviews and observations revealed dominate themes. The results of the Wilcoxon signed ranks test indicated that the students who took part in the AMT at both schools had significant learning gains. We describe the validation and transfer of the analytical methods at the two schools, how learning outcomes are addressed, the POGIL activities and report on student responses to the AMT. The authors gratefully acknowledge the financial support of the NSF (DUE: 1141021 and 1141042) for this project.

Analytical method transfer�development of case studies

248th National Meeting (2014)

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