Nanoparticles are finding increased use in a wide range of emerging technologies, leading to increased interest in understanding how nanoparticles interact with biological membranes and organisms. Nanodiamond is an attractive material to study because it is non-reactive, can be functionalized with various ligands to control its charge state, and because an intrinsic defect, the Nv center, allows nanodiamond to be used as a fluorescent probe imaging by conventional and sub-diffraction imaging methods.  Here, we report on new approaches to controlling the surface chemistry of nanodiamond and how these chemical changes impact the interaction of nanodiamond with lipid bilayers and model biological organisms.

Nanodiamond as a non-reactive probe of nanomaterial-biological interactions

248th National Meeting (2014)

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