Surface enhanced Raman spectroscopy (SERS) has been validated to be a highly accurate and specific tool for the identification, discrimination and potential quantification of different types of chemical and microbiological analytes. However, its application in detection of targeted analytes in foods is still not well developed because the interferences from the complicated food matrices result in spectral deconvolution and interpretation difficult. To separate and enrich analytes from foods before SERS is a major challenge. Here we present two promising �capturing� techniques developed in our laboratory, namely molecularly imprinted polymers and microfluidics, coupled with SERS for a reliable and ultrafast determination of chemical and microbiological hazards in agricultural and food systems. With the availability and progress of portable and handheld Raman spectrometer, the developed �one-step� or �two-step� hybrid SERS nanobiosensor coupled with chemometrics can be applied for on-line and in-field detection of trace level of hazards in foods.

Tandem SERS nanobiosensor for determination of chemical and microbiological hazards in foods

248th National Meeting (2014)

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