Cyprosulfamide (CSA) is an acyl-sulfonamide safener first launched in 2009 for pre- and post-emergence safening in corn. Previous safeners in corn were either just pre-emergence (e.g. dichlormid, benoxacor) or post-emergence (isoxadifen-ethyl; IDF). CSA comes from the exploration and optimization of acyl-sulfonamide safeners conducted by AgrEvo in the mid-1990s using post-emergence safener tests with corn and a sulfonylurea herbicide. Several highly active compounds, including CSA, were identified but there were no clear commercial advantages over IDF which was being developed at the time. After company consolidations, however, new opportunities for the acyl sulfonamides were identified with isoxaflutole and thiencarbazone for which IDF was inadequate. Many acyl sulfonamides were retested with isoxaflutole and CSA emerged as the most active compound and was put into development. Currently, CSA safens a number of Bayer CropScience corn herbicide products such as Balance Flexx�, Adengo� and Corvus�. CSA sets a new benchmark for flexible safening.

Cyprosulfamide: A new benchmark for flexible safening

248th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.