Due to the development of insecticide resistance to existing chemistries and the continuous demand for safer pesticides, a new class of insecticide has been desired. As part of our lead discovery program, random screening was conducted starting from alkynyloxypyrimidine insecticides, which originated from our previous research. A new lead compound was discovered by changing the alkynyloxy group to a triazole ring and identified as a new class of insecticides, azolylpyrimidines. In this poster the structure activity relationship will be discussed. In addition, biological features and synthesis of representative compounds will be also discussed.

Synthesis and insecticidal activity of azolylpyrimidines

248th National Meeting (2014)

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