Perithrins produced by the flowers of pyrethrums are natural pesticides. Pyrithroids are systhesized compounds with similar structure of pyrithrins which were commercialized and widely used as pesticides. These compounds are highly effective to kill insects with low toxicity to mammalians. However, after decades, it was realized that the consequence to environmet such as the pollution of ground water and the toxicity to bees and butterflies. Therefore, it is important to monitor the usage of pyrithroids and their residues in crops.Gas chromatography based analytical methods including GCMS were developed by the pyrithoids producers and regulatory laboratories. The sensitivity of these method were very good. However, due to the high temperature for sample injection, a pyrethroid could be decomposed to another at sample injection step, which would make difficulties for identification. Although some LC-MS methods developed in last decade can overcome the difficulties of GCMS methods, The sensitivity was not enough for regulatory work.This study analyzed 10 frequently detected pyrithroids with new modes of LC-MS/MS instruments. The methods were with high sensitivity for regulatory work. Different sample preparation methods coupled with these instrument methods were tested. The results showed that the new method were faster, reliable and sensitive.

LC-MS/MS method for pyrithroids analysis

248th National Meeting (2014)

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