We present a novel way to generate AgNPs without adding additional reducing agents. In this method we reduced the silver nitrate by utilizing the epoxy group on the polymer (glycidyl methacrylate) (PGMA) sub-microspheres, which upon ring opening become hydroxyl group enabling polymer itself to act as reducing agent. The AgNPs formed by the polymer are successfully coated on the polymer spheres,see the HRTEM image . Size of the AgNPs is controllable by optimizing time and concentration of the silver nitrate solution.Production of AgNPs without adding additional reducing agent, can transform the production of AgNPs saving time and cost along with reducing toxic metabolites. Furthermore we tested antibacterial and anticancer properties of AgNPs coated PGMA composite produced by this method using E.Coli and cancer cell line KB-31& HepG2. These AgNPs polymer composite successfully kill both bacteria and cancer cells confirming the active biological properties of the AgNPs produced by auto-reduction. Also the biological activities of the AgNPs was found to better against both the cancer cells lines KB-31 and HepG2 cells with a concentration of 9.9 �g/mL comparing to the pure AgNPs without composite of 20�g/mL.

Auto-reduction of a novel type of polymer composite coated with silver nanoparticles and its application

248th National Meeting (2014)

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