A series of novel 3-sulfonylisoxazoline derivatives prepared in the following scheme showed good herbicidal activity against annual weeds. The 3-sulfonylisoxazoline derivatives consisting of isoxazoline and benzene rings have unique physical characteristics that allow these derivatives to provide stable efficacy under flooded rice culture systems and prevent the risk of leaching into groundwater. The optimization of the performance of the compounds as a new herbicide for use in rice led to the discovery of Fenoxasulfone. In this poster, the structure � activity relationship, synthetic methods and influence of physicochemical properties will be discussed. 

3-Sulfonylisoxazoline derivatives as novel herbicides

248th National Meeting (2014)

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