The feasibility of using residue data developed in one geographic region to suffice for other regions in the establishment of Maximum Residue Limits (MRLs) was studied in 27 field trial locations representing field tomato production regions from 22 countries, six continents and multiple climates. In supervised field trials, using identical application equipment and pre-measured amount of chemical, a single application of four chemicals (mandipropamid, difenoconazole, thiamethoxam and lambda-cyhalothrin) were sprayed on field tomato. Fruit were harvested at 0, 1 & 3 days after application, frozen and shipped to one analytical laboratory where chemical and metabolites were analyzed. Residue values for all four chemicals were compared between sites, countries, continents and climates. The amount of residue on tomatoes is comparable across different continents and climates. This initial data set supports the concept that using data developed in one country to reduce the data requirements in another country is possible, while providing regulatory agencies a more robust data set. This mixed data set is similar to the way the US and Canada has accepted data from each other's countries to support MRL establishment. The data from this study also shows the potential for data from various supervised field trials throughout the world to be combined into a single study that can be submitted to multiple regulatory authorities to support harmonized MRLs in multiple countries and regions. The authors thank the United States Department of Agriculture-Foreign Agriculture Service for funds through it Technical Assistance for Specialty Crops for funding.

Use of global residue data sets to facilitate establishment of harmonized maximum residue levels

248th National Meeting (2014)

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