Compounds of the type shown below are examples of a new chemical class with potent activity against a broad spectrum of diseases, comparable to commercialised standards. Aspects of the discovery, synthesis, biology and structure-activity relationships together with design considerations will be presented.

Synthesis and fungicidal activity of quinolin-6-yloxyacetamides: A novel class of tubulin polymerization inhibitors

248th National Meeting (2014)

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