Firstly, the importance of crop protection compounds will be briefly presented and the research methodologies at Bayer CropScience (BCS) to develop active molecules will be introduced with analogies to the pharmaceutical Industry. The key role of fluorinated heterocycles in Agrochemicals will then be highlighted and the need to constantly find new fluorinated substituted heterocycles will be expressed. To illustrate some recent advances in fluorinated groups that can be applied to Agrochemistry, the presentation will focus on the development of trifluoromethoxy containing heterocycles, namely 2,3 or 4-CF3O-containing pyridines, 4-CF3O containing pyrazoles.  As an illustration, several synthetic pathways and further functionalizations to these noteworthy fluorinated heterocycles will be given.

Rare fluorinated substituents for application in agrochemistry: Fruitful collaboration between Bayer CropScience and universities

248th National Meeting (2014)

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