Solid phase micro-extraction (SPME), coupled with NCI-GC-MS analysis, has been applied to the analysis of synthetic pyrethroids in aqueous solutions.   This technology detects only freely dissolved chemical, in contrast to classical liquid-liquid extraction (LLE) which detects the total chemical in the aqueous phase, including that associated with dissolved organic carbon, particulates, and material bound to vessel walls.   The very rapid adsorption of pyrethroids to vessel walls makes the use of calibration standards problematic for SPME analyses.  During studies to generate comparative data on LLE-based and SPME-based sediment adsorption (KD and KOC coefficients), data have been generated to quantify the scope of this confounding factor.  Replicated measurements of freely dissolved pyrethroid concentrations in aqueous solutions equilibrated with treated sediments are highly reproducible, confirming the utility of SPME for environmental samples -- especially when used with stable isotope-labeled internal standards. Various approaches have been developed to minimize the impact of calibration standard wall adsorption and are reported herein.

Refinement of analytical techniques for solid phase micro-extraction (SPME) measurement of pyrethroid concentrations in aqueous systems

248th National Meeting (2014)

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