The behavior of biological systems varies in space and time.  The BONCAT (bioorthogonal non-canonical amino acid tagging) method provides a means by which investigators can probe the heterogeneous nature of protein synthesis in complex biological systems, including live animals.  This lecture will examine the scope and limitations of the BONCAT method, with examples drawn from neurobiology, cancer biology and microbiology.

Time-resolved, cell-selective analysis of protein synthesis in complex biological systems

248th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.