Nanoparticles are being applied to various fields due to their unique properties. However, with the anticipated increase in nanoparticle use, the risks of nanoparticle exposure to ecosystems need to be assessed. As the mechanism of toxicity remains largely unclear, untargeted, sensitive and fundamental studies evaluating biological response to nanomaterial exposure are needed. This research seeks to assess and compare the toxicity of functionalized gold nanoparticles on gene expression changes in Shewanella oneidensis MR-1, a beneficial bacteria species in the ecosystem, and Daphnia magna, a water flea used as a model organism in aquatic toxicology, aimed at understanding the fundamental molecular mechanism underlying nanotoxicity across different species.

Comparative study of functionalized gold nanoparticle toxicity on bacteria and Daphnia gene expression

248th National Meeting (2014)

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