We have successfully synthesized e-caprolactone-based elastomers modified with cholesteric-type liquid crystal units (LC-bioscaffolds) as new composite materials as a promising strategy for tissue engineering. Bioscaffolds are promising composite materials for the replacement of diseased/damaged human tissues. Most of these materials are engineered so they could provide support, adherence and growth of cells under physiological conditions. The presence liquid crystalline polymeric scaffolds would enhance mechanical properties within the scaffold and promote superior, stimuli-responsive surface properties for cell attachment. Our materials are engineered so they could not only be biocompatible and biodegradable but can also provide support, adherence and growth of cells under physiological conditions, as well as increasing their biomechanical functionality. The properties of these smart responsive scaffolds (or SRS) can be tuned by varying factors such as hydrophobicity as viable candidates for tissue regeneration to which cells can attach, differentiate and proliferate.

Biodegradable liquid crystal caprolactone-based thin film elastomers

248th National Meeting (2014)

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