Polymerization of glycolide was initiated at the surface of thermally pretreated anorganic mammalian bone. Detailed synthetic procedures and characterization will be presented. An average compressive strength of 361 MPa was observed for the composite composed of anorganic bone and polyglycolide (AB/PGA) templated from bovine femurs. This composite exhibits a compressive strength that is greater than that of human bone (167 MPa), and greater than materials previously developed by our lab, such as the composite of anorganic bone and poly-L-lactide (AB/PLLA) (194 MPa). Additionally, the compressive modulus of AB/PGA (14.5 GPa) more closely matches that of human bone (17 GPa), than does the compressive modulus of AB/PLLA (8.8 GPa).

Synthesis and characterization of anorganic bone/polyglycolide composites

249th National Meeting (2015)

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