The tumor-preventative effects of the biologically created quercetin chemical have historically been studied and found to be not efficient enough to be used as a chemotherapeutic drug. Amine and methoxy substituted derivatives of quercetin are being synthesized and tested in seeking a new molecule with better applications as a chemotherapeutic drug. Synthesized derivatives are also tested in conjunction with resveratrol—a second natural compound found to have anti-tumor effects—for a synergistic effect. The synthesized molecules are tested against several separate mouse lines, one that is a metastatic cell culture (T3HA), a non-metastatic cell culture (T2A), and a normal cell line (NIH SWISS).

Study of antitumor effects of quercetin and amine or methoxy polysubstituted derivatives on metastatic and non-metastatic mouse cells

249th National Meeting (2015)

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