A new water-soluble carboxylic-functionalized chemo-sensor 1 was designed and synthesized. 1 exhibited the selective fluorescence enhancement toward aluminum ions in aqueous solution. The binding mode of the 1-Al3+ complex was determined to be a 1:1 complexation stoichiometry through Job plot, ESI-mass spectrometry analysis, and 1H NMR titration. In addition, in vitro studies with fibroblasts showed fluorescence in the presence of both the receptor 1 and Al3+.

Water-soluble chemosensor for detecting Al3+ in aqueous media and living cells

249th National Meeting (2015)

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