Silver nanoparticles improve sensitivity in Surface-Enhanced Raman Spectroscopy (SERS). However, these nanoparticles have limitations due to the wavelength they absorb when applied in biological SERS analysis. To address this problem, silica-core nanoparticles have been proposed to help silver nanoparticles absorb greater wavelength. This project intends to synthesize nanoparticles that have a silica core and a silver shell, and this process involves three steps: (1) synthesis of the silica core, (2) attachment of silver seeds to the surface of the silica core, and (3) growth of the silver shell on the silica core. The size and the shape of the nanoparticles will be analyzed using scanning electron microscopy (SEM) and UV spectroscopy in order to determine the optimum dimensions. The preparation and the characterization of core and shell nanoparticles were determined as a result of this experiment.

Optimization of silver shell and silica core nanoparticles as SERS active substrate

249th National Meeting (2015)

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