The antibacterial properties of Organic Nanoparticles (ONPs) of lipoic acid and the corresponding doped ONPs/Ag and ONPs/Au were tested against bacterial strains (Staphylococcus aureus, Bacillus cereus, Escherichia coli and Salmonella typhi) by qualitative and quantitative assays. Minimal inhibitory concentration (MIC) results show that ONPs are more effective in growth control for Gram positive bacteria than for Gram-negative ones. Although all the synthesized NPs act as antibacterial agents, ONPs/Ag NPs inhibit the bacterial growth increases than other nanoparticles with a major effect over Gram negative bacteria. The order of bacterial cell growth inhibition was ONPs/Ag &gt; ONPs &gt; ONPs/Au. We also analyzed the morphology of bacterial cells treated with NPs by SEM.

Lipoic acid organic nanoparticles (ONPs) for bacterial inhibition: Synthesis, characterization, and antibacterial studies of doped and undoped ONPs with Ag/Au NPs

249th National Meeting (2015)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.