The Hagemann’s ester is a tool for natural product synthesis. The capability of synthesizing natural products with the use of a non-metal catalyst has been a cause to further research the ester. The reaction mechanism for synthesizing Hagemann’s ester has been investigated and the synthesis was found to depend on the amine used, along with the addition of a strong base. The ester was then investigated to determine successful use in the synthesis of a highly substituted analine with a non-metal catalyst, in a one-pot organocatalytic reaction. A high yield of C-3 akylation onto the product was anticipated. The catalyst researched was pyrrolidine, and the primary reactant researched was nitrosobenzene.

Investigation of the role of Hagemann’s ester as a catalyst for natural product synthesis

249th National Meeting (2015)

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