As the medicinal properties of cannabis continue to be studied and the legalization of medicinal and recreational cannabis continues, the demand of cannabis products and extracts will continue to rise. As a result, there will be continued pressure placed on analytical laboratories to provide safe and effective testing with a much higher throughput. In addition, due to the uncertainty of the market, it may not be financially feasible to upgrade to the most recent technologies and costly instruments. In this presentation, we will illustrate how a highly selective stationary phase combined with superficially porous particle technology can be quickly utilized to increase sample throughput on instrumentation currently employed in cannabis laboratories. We will illustrate examples of increasing sample throughput for HPLC and LC-MS/MS assays, by significantly decreasing analysis times, without sacrificing data quality. In comparison, we will correlate these results to those achieved by more costly UHPLC. Key Topics: · Examples of how customers can use column chemistry and composition to greatly increase sample throughput without extreme cost · Using Superficially Porous LC columns to decrease analysis times – get UHPLC performance out of an HPLC. · Using the selectivity of LC phases designed specifically for cannabis analysis to provide greater resolution and data quality · Using optimized column dimensions to increase the speed of cannabis analysis

Increasing sample throughput of Cannabis analyses on any LC system

249th National Meeting (2015)

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