In this talk, we will show how linear and nonlinear infrared spectroscopic techniques can be used to quantify various physical properties of membranes and to reveal functionally relevant structural and dynamic information of membrane proteins. Specifically, we will discuss how site-specific infrared probes can be used to determine the local electrostatics and hydration status of membranes and how two-dimensional infrared spectroscopy can be used to provide a better understanding of the proton conducting mechanism of the M2 channel of influenza A virus.<br/>

Infrared study of membranes and membrane proteins

249th National Meeting (2015)

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