The quest for small molecule drugs with the efficacy and safety of biologics, particularly in the area of autoimmune and inflammatory diseases, has been a major effort in the pharmaceutical industry for the last two decades. While there have been notable achievements, identifying molecules in the efficacy-safety ‘sweet spot’ has been a significant challenge. This presentation will review several past approaches that have met with various levels of success as well as describe the significant potential for current and future directions.

In search of small molecule modulators for the treatment of autoimmune and inflammatory diseases

249th National Meeting (2015)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.