<br/>The selectivity of DNA recognition inspires an elegant protocol for designing versatile nanoparticle (NP) assemblies. We use molecular dynamics simulations to analyze dynamic aspects of the assembly process and identify ingredients that are key to a successful assembly of NP superlattices through DNA hybridization. A scale-accurate coarse-grained model faithfully captures the relevant contributions to the kinetics of the DNA hybridization process and is able to recover all experimentally reported to date binary<br/>Superlattices. With multi-scale modeling we show that through very slow cooling, DNA functionalized nanoparticles can assemble into superlattices with a specific crystal habit, providing a nanoscale analogue to the crystallization behavior exhibited by conventional atomic crystals. We also describe directed assembly of nanoparticles at interfaces.

DNA-functionalized nanoparticle assembly

249th National Meeting (2015)

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